Structure of PDB 7rje Chain M

Receptor sequence
>7rjeM (length=181) Species: 237561 (Candida albicans SC5314) [Search protein sequence]
NYQQPDYSSYLNNKSGQGSRNFTYFMVGSMGLLSAAGAKSTVEAFLSSFA
ASADVLAMAKVEVKLGAIPEGKNVIIKWQGKPVFIRHRTADEIEEANQVD
IKTLRDPQNDADRVKKPEWLIMLGICTHLGCVPIGEAGDFGGWFCPCHGS
HYDISGRIRKGPAPLNLEIPEYDFTDDETLL
3D structure
PDB7rje Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
ChainM
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.8: quinol--cytochrome-c reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES M H158 L159 C175 C177 H178 H128 L129 C145 C147 H148
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006412 translation
GO:0009060 aerobic respiration
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0045275 respiratory chain complex III

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Cellular Component
External links
PDB RCSB:7rje, PDBe:7rje, PDBj:7rje
PDBsum7rje
PubMed34525326
UniProtA0A1D8PJX3|RIP1_CANAL Cytochrome b-c1 complex subunit Rieske, mitochondrial (Gene Name=RIP1)

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