Structure of PDB 7md5 Chain M

Receptor sequence
>7md5M (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
AAAKELEESSFRKTFEDYLHNVVFVPSPSR
3D structure
PDB7md5 Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
ChainM
Resolution5.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide M D707 H710 F714 V715 S717 P718 R720 D17 H20 F24 V25 S27 P28 R30
External links
PDB RCSB:7md5, PDBe:7md5, PDBj:7md5
PDBsum7md5
PubMed35177603
UniProtP06213|INSR_HUMAN Insulin receptor (Gene Name=INSR)

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