Structure of PDB 7md5 Chain M
Receptor sequence
>7md5M (length=30) Species:
9606
(Homo sapiens) [
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AAAKELEESSFRKTFEDYLHNVVFVPSPSR
3D structure
PDB
7md5
Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Chain
M
Resolution
5.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
M
D707 H710 F714 V715 S717 P718 R720
D17 H20 F24 V25 S27 P28 R30
External links
PDB
RCSB:7md5
,
PDBe:7md5
,
PDBj:7md5
PDBsum
7md5
PubMed
35177603
UniProt
P06213
|INSR_HUMAN Insulin receptor (Gene Name=INSR)
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