Structure of PDB 7lyb Chain M

Receptor sequence
>7lybM (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
SALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN
QKKGPSQCPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDT
3D structure
PDB7lyb Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
ChainM
Resolution3.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN M C24 C44 C47 C21 C41 C44
BS02 ZN M C39 H41 C61 C36 H38 C58
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006974 DNA damage response

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Molecular Function
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Biological Process
External links
PDB RCSB:7lyb, PDBe:7lyb, PDBj:7lyb
PDBsum7lyb
PubMed34321665
UniProtP38398|BRCA1_HUMAN Breast cancer type 1 susceptibility protein (Gene Name=BRCA1)

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