Structure of PDB 7ccr Chain M

Receptor sequence
>7ccrM (length=79) Species: 9606 (Homo sapiens) [Search protein sequence]
DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYT
EHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB7ccr Structural basis for nucleosome-mediated inhibition of cGAS activity.
ChainM
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna M P32 R36 P9 R13
BS02 dna M R45 I46 S47 G48 R78 K79 T80 R22 I23 S24 G25 R55 K56 T57
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:7ccr, PDBe:7ccr, PDBj:7ccr
PDBsum7ccr
PubMed33051594
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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