Structure of PDB 6zxe Chain M

Receptor sequence
>6zxeM (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
GVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEP
MYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCV
VVKDYGKESQAKDVIEEYFKCKK
3D structure
PDB6zxe Structural basis for the final steps of human 40S ribosome maturation.
ChainM
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna M R33 G34 I35 R36 E37 K40 E58 N82 L91 R101 K102 C106 S107 C108 R24 G25 I26 R27 E28 K31 E49 N73 L82 R92 K93 C97 S98 C99
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zxe, PDBe:6zxe, PDBj:6zxe
PDBsum6zxe
PubMed33208940
UniProtP25398|RS12_HUMAN Small ribosomal subunit protein eS12 (Gene Name=RPS12)

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