Structure of PDB 6y5d Chain M

Receptor sequence
>6y5dM (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVGLFEDTNLAAIHAKRVTIMPKDIQLARRIRGE
3D structure
PDB6y5d Structural mechanism of cGAS inhibition by the nucleosome.
ChainM
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna M R43 R84 F85 R117 V118 R5 R46 F47 R79 V80
BS02 dna M R41 Y42 G45 V47 A48 R64 R3 Y4 G7 V9 A10 R26
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6y5d, PDBe:6y5d, PDBj:6y5d
PDBsum6y5d
PubMed32911482
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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