Structure of PDB 6xr0 Chain M

Receptor sequence
>6xr0M (length=683) Species: 9606 (Homo sapiens) [Search protein sequence]
MEVRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQ
EADAITLDGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVT
IDTLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGG
SCVPGAGETSYSESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEG
AGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELLCRDGSRADVTEWRQ
CHLARVPAHAVVVRADTDGGLIFRLLNEGQRLFSSSFQMFSSEAYGQKDL
LFKDSTSELVPIATQTYEAWLGHEYLHAMKGLLCDPNRLPPYLRWCVLST
PEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGE
DIYTAGKTYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGK
RSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNN
PKNYPSSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFV
RHTTVFDNTNGHNSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIP
PHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFKMFDSSNYHGQDLLF
KDATVRAVPVGEKTTYRGWLGLDYVAALEGMSS
3D structure
PDB6xr0 Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe.
ChainM
Resolution3.064 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE M D78 Y107 Y210 H279 D58 Y87 Y190 H259
BS02 BCT M D78 T132 R136 V138 Y210 D58 T112 R116 V118 Y190
Gene Ontology
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

View graph for
Cellular Component
External links
PDB RCSB:6xr0, PDBe:6xr0, PDBj:6xr0
PDBsum6xr0
PubMed
UniProtP08582|TRFM_HUMAN Melanotransferrin (Gene Name=MELTF)

[Back to BioLiP]