Structure of PDB 6weo Chain M

Receptor sequence

>6weoM (length=201) Species: 10090 (Mus musculus) [Search protein sequence]

LLQHVKFQSSNFENILTWDGGPASTSDTVYSVEYKKYGERKWLAKAGCQR
ITQKFCDLTMETRDHQEFYYAKVTAVSAGGPPVTKMTDRFSSLQHTTIKP
PDVTCIPKVRSIQMLVHPTLTPVLSEDGHQLTLEEIFHDLFYRLELHVNH
TYQMHLEGKQREYEFLGLTPDTEFLGSITILTPILSKESAPYVCRVKTLP
D

3D structure

PDB

6weo The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.

Chain

Resolution

2.6 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FUC	M	L191 T192 F197	L168 T169 F174

External links

PDB	RCSB:6weo, PDBe:6weo, PDBj:6weo
PDBsum	6weo
PubMed	33852830
UniProt	Q80XZ4\|I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 (Gene Name=Il22ra1)

[Back to BioLiP]