Structure of PDB 6v4n Chain M

Receptor sequence
>6v4nM (length=391) Species: 11520 (Influenza B virus) [Search protein sequence]
SPSRWTYPRLSCPGSTFQKALLISPHRFGETKGNSAPLIIREPFIACGPK
ECKHFALTHYAAQPGGYYNGTREDRNKLRHLISVKLGKIPTVENSIFHMA
AWSGSACHDGREWTYIGVDGPDSNALLKIKYGEAYTDTYHSYAKNILRTQ
ESACNCIGGDCYLMITDGPASGISECRFLKIREGRIIKEIFPTGRVKHTE
ECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTKTYLDT
PRPNDGSITGPCESDGDEGSGGIKGGFVHQRMASKIGRWYSRTMSKTKRM
GMGLYVKYDGDPWTDSEALALSGVMVSMEEPGWYSFGFEIKDKKCDVPCI
GIEMVHDGGKTTWHSAATAIYCLMGSGQLLWDTVTGVNMTL
3D structure
PDB6v4n Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
ChainM
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA M D293 T297 D324 G344 G346 D218 T222 D249 G269 G271
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v4n, PDBe:6v4n, PDBj:6v4n
PDBsum6v4n
PubMed32976769
UniProtA0A1S5RAG6

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