Structure of PDB 6swa Chain M

Receptor sequence

>6swaM (length=203) Species: 10090 (Mus musculus) [Search protein sequence]

GAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRL
GYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSV
AEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWI
TKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLH
RYR

3D structure

PDB

6swa Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	M	G2 Y4 Q8 R12 K14 Q15 W28 R31 S34 A35 P40 R41 R44 K47 R49 R50 L51 K54 A55 Q57 R65 R67 R68 R71 K72 R73 P74 K77 Y81 G82 K83 V85 H86 H87 V89 N90 Q91 K93 F94 A95 R96 L98 V101 E104 R105 R108 A112 S125 Y127 K128 F138 R144 W150 P154 H156 K157 M161 R162 S166 R169 K170 R172 K176 G177 H178 K179 H181 H182 I184 G185 G186 S187 R189 W192 R193 R195 H201 R202 Y203 R204	G1 Y3 Q7 R11 K13 Q14 W27 R30 S33 A34 P39 R40 R43 K46 R48 R49 L50 K53 A54 Q56 R64 R66 R67 R70 K71 R72 P73 K76 Y80 G81 K82 V84 H85 H86 V88 N89 Q90 K92 F93 A94 R95 L97 V100 E103 R104 R107 A111 S124 Y126 K127 F137 R143 W149 P153 H155 K156 M160 R161 S165 R168 K169 R171 K175 G176 H177 K178 H180 H181 I183 G184 G185 S186 R188 W191 R192 R194 H200 R201 Y202 R203
BS02	rna	M	R38 Q57 V60 Y62 D136 H139	R37 Q56 V59 Y61 D135 H138

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0045471	response to ethanol
GO:0140236	translation at presynapse
GO:0140242	translation at postsynapse

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0031672	A band
GO:0044391	ribosomal subunit
GO:0045202	synapse
GO:0098793	presynapse
GO:0098794	postsynapse
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6swa, PDBe:6swa, PDBj:6swa
PDBsum	6swa
PubMed	33357414
UniProt	Q9CZM2\|RL15_MOUSE Large ribosomal subunit protein eL15 (Gene Name=Rpl15)

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