Structure of PDB 6mu3 Chain M

Receptor sequence

>6mu3M (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVKAGGSLILSCGVSNFRISAHTMNWVRRVPGGGLEWVAS
ISTSSTYRDYADAVKGRFTVSRDDLEDFVYLQMHKMRVEDTAIYYCARKG
SDRLSDNDPFDAWGPGTVVTVSPASTKGPSVFPLAPSTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICN
VNHKPSNTKVDKKVEP

3D structure

PDB

6mu3 Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

Chain

Resolution

2.327 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MAN	M	A31 D100B	A31 D106
BS02	MAN	M	A31 H32 T33 K95 G96 S100A D100B N100C D100D	A31 H32 T33 K99 G100 S105 D106 N107 D108

External links

PDB	RCSB:6mu3, PDBe:6mu3, PDBj:6mu3
PDBsum	6mu3
PubMed	16174734
UniProt	P0DOX5\|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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