Structure of PDB 6huf Chain M

Receptor sequence
>6hufM (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKTIYRNDKR
IKLQLWDTAGLERFRSLTTAFFRDAMGFLLLFDLTNEESFLNVRNWISQL
KTHAYSENPDIVLCGNKSDLEDERVVAAAEARQLAEHYGIPYFETSAANG
TNISQAIEMLLDLIMKRMERS
3D structure
PDB6huf Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a.
ChainM
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG M T23 T41 T16 T34
BS02 GNP M S18 G21 K22 T23 S24 S36 T41 G67 N123 K124 D126 L127 S153 S11 G14 K15 T16 S17 S29 T34 G60 N116 K117 D119 L120 S146
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6huf, PDBe:6huf, PDBj:6huf
PDBsum6huf
PubMed30950405
UniProtP51159|RB27A_HUMAN Ras-related protein Rab-27A (Gene Name=RAB27A)

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