Structure of PDB 6cxg Chain M

Receptor sequence

>6cxgM (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVKAGGSLILSCGVSNFRISAHTMNWVRRVPGGGLEWVAS
ISTSSTYRDYADAVKGRFTVSRDDLEDFVYLQMHKMRVEDTAIYYCARKG
SDRLSDNDPFDAWGPGTVVTVSPASTKGPSVFPLAPSSKSTSGGTAALGC
LVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG
TQTYICNVNHKPSNTKVDKKVEPK

3D structure

PDB

6cxg Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.

Chain

Resolution

2.298 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	M	R28 E75 D76 F77	R28 E76 D77 F78
BS02	peptide	M	T55 Y56 R57 Y59 K64 G65 F67 T68	T56 Y57 R58 Y60 K65 G66 F68 T69
BS03	MAN	M	A31 D100B	A31 D106
BS04	MAN	M	A31 H32 T33 K95 S100A D100B N100C D100D	A31 H32 T33 K99 S105 D106 N107 D108

External links

PDB	RCSB:6cxg, PDBe:6cxg, PDBj:6cxg
PDBsum	6cxg
PubMed	30834312

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