Structure of PDB 5yi3 Chain M

Receptor sequence
>5yi3M (length=144) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence]
SLANQIDQFLGTIMQFAENKHEILLGKSESDVKLTSTQEHILMLLAEQIS
TNAKIAEKLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEKAV
PVAKEHATHHEKTLSTYQELGNKFTDEEQEVISKFLSALTEEFQ
3D structure
PDB5yi3 Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
ChainM
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna M T37 T39 I63 S64 A67 K70 T35 T37 I61 S62 A65 K68 PDBbind-CN: Kd=0.55uM
BS02 dna M N54 A55 P65 A66 T69 N52 A53 P63 A64 T67 PDBbind-CN: Kd=0.55uM
BS03 dna M T53 V92 T51 V90 PDBbind-CN: Kd=0.55uM
BS04 ZN M E24 H42 H108 H112 E22 H40 H106 H110
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5yi3, PDBe:5yi3, PDBj:5yi3
PDBsum5yi3
PubMed29229866
UniProtQ9CDU5

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