Structure of PDB 5b6b Chain M

Receptor sequence
>5b6bM (length=173) Species: 10090 (Mus musculus) [Search protein sequence]
KHAEADLNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEE
SCPVMSAGPKYEYHWPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPF
PKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFV
QEFNLIDRRELAPLQELIEKLTS
3D structure
PDB5b6b Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
ChainM
Resolution3.536 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN M C84 H161 H166 C52 H121 H126
Gene Ontology
Molecular Function
GO:0019209 kinase activator activity
GO:0019900 kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0031952 regulation of protein autophosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5b6b, PDBe:5b6b, PDBj:5b6b
PDBsum5b6b
PubMed27335147
UniProtQ8BPB0|MOB1B_MOUSE MOB kinase activator 1B (Gene Name=Mob1b)

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