Structure of PDB 5a2q Chain M

Receptor sequence
>5a2qM (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
GVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEP
MYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCV
VVKDYGKESQAKDVIEEYFKCKK
3D structure
PDB5a2q Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution
ChainM
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna M R33 G34 I35 R36 E37 K40 Y61 L91 G105 C106 S107 C108 R24 G25 I26 R27 E28 K31 Y52 L82 G96 C97 S98 C99
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:5a2q, PDBe:5a2q, PDBj:5a2q
PDBsum5a2q
PubMed26155016
UniProtP25398|RS12_HUMAN Small ribosomal subunit protein eS12 (Gene Name=RPS12)

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