Structure of PDB 4zux Chain M

Receptor sequence
>4zuxM (length=103) Species: 8355 (Xenopus laevis) [Search protein sequence]
TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILEL
AGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVL
LPK
3D structure
PDB4zux Structural basis for histone H2B deubiquitination by the SAGA DUB module.
ChainM
Resolution3.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna M T16 R17 R20 R29 R32 R42 R77 T1 R2 R5 R14 R17 R27 R62
BS02 dna M R29 R35 R42 V43 G44 A45 K75 T76 R14 R20 R27 V28 G29 A30 K60 T61
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4zux, PDBe:4zux, PDBj:4zux
PDBsum4zux
PubMed26912860
UniProtP06897|H2A1_XENLA Histone H2A type 1

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