Structure of PDB 4r7z Chain M

Receptor sequence
>4r7zM (length=316) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
PEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKL
PDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSAAAAAAAAAA
AAAAAAAAAAAAAAAAAGGYALIDELDKMSDRDRSVIHEALEQQTISISK
AGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVL
IDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPV
ISEEAMEEIEKYYVRMRKSPITARQLEALIRLSEAHARMRLSPIVTREDA
REAIKLMEYTLKQIAM
3D structure
PDB4r7z Analysis of the crystal structure of an active MCM hexamer.
ChainM
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP M I290 Y291 G331 A333 K334 S335 Q336 V847 I851 I28 Y29 G69 A71 K72 S73 Q74 V212 I216
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:4r7z, PDBe:4r7z, PDBj:4r7z
PDBsum4r7z
PubMed25262915
UniProtQ8U3I4

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