Structure of PDB 3u5z Chain M

Receptor sequence
>3u5zM (length=320) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
SMITVNEKEHILEQKYRPSTIDECILPAFDKETFKSITSKGKIPHIILHS
PSPGTGKTTVAKALCHDVNADMMFVNGSDCKIDFVRGPLTNFASAASFDG
RQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQ
SRCRVITFGQPTDEDKIEMMKQMIRRLTEICKHEGIAIADMKVVAALVKK
NFPDFRKTIGELDSYSSKGVLDAGILSLVTNDRGAIDDVLESLKNKDVKQ
LRALAPKYAADYSWFVGKLAEEIYSRVTPQSIIRMYEIVGENNQYHGIAA
NTELHLAYLFIQLACEMQWK
3D structure
PDB3u5z How a DNA polymerase clamp loader opens a sliding clamp.
ChainM
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna M K80 I81 R85 R111 K81 I82 R86 R112
BS02 08T M E12 R16 I24 P52 G53 T54 G55 K56 T57 T58 E108 N139 F204 R205 E13 R17 I25 P53 G54 T55 G56 K57 T58 T59 E109 N140 F205 R206
BS03 MG M T57 E108 T58 E109
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication
Cellular Component
GO:0005663 DNA replication factor C complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3u5z, PDBe:3u5z, PDBj:3u5z
PDBsum3u5z
PubMed22194570
UniProtP04526|LOADL_BPT4 Sliding-clamp-loader large subunit (Gene Name=44)

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