Structure of PDB 3ias Chain M

Receptor sequence
>3iasM (length=377) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MTLNVGGVLRLMVTLSGEEVLEVVPHIGYLHTGFEKTMEHRTYLQNITYT
PRMDYLHSFAHDLAYALAVEKLLGAVVPPRAETIRVILNELSRLASHLVF
LGTGLLDLGALTPFFYAFRERETILDLFEWVTGQRFHHNYIRIGGVKEDL
PEEFVPELKKLLEVLPHRIDEYEALFAESPIFYERARGVGVIPPEVAIDL
GLTGGSLRASGVNYDVRKAYPYSGYETYTFDVPLGERGDVFDRMLVRIRE
MRESVKIIKQALERLEPGPVRDPNPQITPPPRHLLETSMEAVIYHFKHYT
EGFHPPKGEVYVPTESARGELGYYIVSDGGSMPYRVKVRAPSFVNLQSLP
YACKGEQVPDMVAIIASLDPVMGDVDR
3D structure
PDB3ias Structural basis for the mechanism of respiratory complex I
ChainM
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 M R84 H169 R52 H137
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
GO:0051287 NAD binding
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3ias, PDBe:3ias, PDBj:3ias
PDBsum3ias
PubMed19635800
UniProtQ56220|NQO4_THET8 NADH-quinone oxidoreductase subunit 4 (Gene Name=nqo4)

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