Structure of PDB 3d1n Chain M

Receptor sequence
>3d1nM (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
NMEEIREFAKNFKIRRLSLGLTQTQVGQAMTATEGPAYSQSAISRFEKLD
ITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFT
PQAIEALNAYFEKNPLPTGQEITEMAKELNYDREVVRVWFSNRRQTLKNT
3D structure
PDB3d1n Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
ChainM
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna M R158 T164 Q165 Q182 S183 S186 K190 R235 K236 R237 R238 T239 F241 W281 N284 R16 T22 Q23 Q40 S41 S44 K48 R93 K94 R95 R96 T97 F99 W139 N142
BS02 dna M A179 S181 S183 R235 R237 R238 Q287 A37 S39 S41 R93 R95 R96 Q145
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3d1n, PDBe:3d1n, PDBj:3d1n
PDBsum3d1n
PubMed19450691
UniProtQ14863|PO6F1_HUMAN POU domain, class 6, transcription factor 1 (Gene Name=POU6F1)

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