Structure of PDB 2xa7 Chain M

Receptor sequence
>2xa7M (length=428) Species: 10116 (Rattus norvegicus) [Search protein sequence]
MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNI
ARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEEN
IKNNFVLIYELLDEILDFGYPQNSETGALKTFITQHQTKEEQSQITSQVT
GQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYL
SGMPECKFGMNDKIVIESMEQKLISEEDLGKQSIAIDDCTFHQCVRLSKF
DSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVI
KSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKR
MAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVF
EPKLNYSDHDVIKWVRYIGRSGIYETRC
3D structure
PDB2xa7 A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
ChainM
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide M F174 D176 V412 K431 W432 V433 R434 F168 D170 V394 K413 W414 V415 R416
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2xa7, PDBe:2xa7, PDBj:2xa7
PDBsum2xa7
PubMed20603002
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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