Structure of PDB 1uw6 Chain M

Receptor sequence
>1uw6M (length=208) Species: 6523 (Lymnaea stagnalis) [Search protein sequence]
EFDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVD
VVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLT
PQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSRE
ISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSL
NFRKKGRS
3D structure
PDB1uw6 Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures
ChainM
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NCT M W53 M114 W54 M115 MOAD: Kd=45.2nM
BindingDB: Ki=316.23nM,Kd=316nM
BS02 NCT M Y89 W143 Y185 C187 Y192 Y90 W144 Y186 C188 Y193 MOAD: Kd=45.2nM
BindingDB: Ki=316.23nM,Kd=316nM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1uw6, PDBe:1uw6, PDBj:1uw6
PDBsum1uw6
PubMed15046723
UniProtP58154|ACHP_LYMST Acetylcholine-binding protein

[Back to BioLiP]