Structure of PDB 8xt3 Chain Lv

Receptor sequence
>8xt3Lv (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
YKTKPTHGIGKYKHLIKAEVRAINLGTDYEYGVLNIHLTAYDMTLAESYA
QYVHNLCNSLSIKVEESYAMPTKTIEVLQLQMLLDSVLTTHERVVQISGL
SATFAEIFLEIIQSSLPEGVRLSVKEHTEED
3D structure
PDB8xt3 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainLv
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Lv Y48 K49 T50 K51 I56 G57 K58 Y59 K60 Y1 K2 T3 K4 I9 G10 K11 Y12 K13
BS02 rna Lv E104 Q108 H111 N112 N115 S124 R155 E47 Q51 H54 N55 N58 S67 R93
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8xt3, PDBe:8xt3, PDBj:8xt3
PDBsum8xt3
PubMed38942792
UniProtQ96GC5|RM48_HUMAN Large ribosomal subunit protein mL48 (Gene Name=MRPL48)

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