Structure of PDB 7xnx Chain Lr

Receptor sequence
>7xnxLr (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
SAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGV
EPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNK
YRPDLRMAAIRRASAILRSQKPVMV
3D structure
PDB7xnx A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia.
ChainLr
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna Lr W7 R11 S15 K19 K22 Q23 T24 K33 R35 N36 S37 F38 R39 R66 R67 S68 T80 K84 R87 R94 H95 M96 R98 K99 N100 D105 R107 M108 R112 R119 W6 R10 S14 K18 K21 Q22 T23 K32 R34 N35 S36 F37 R38 R65 R66 S67 T79 K83 R86 R93 H94 M95 R97 K98 N99 D104 R106 M107 R111 R118
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0030425 dendrite
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0044297 cell body
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7xnx, PDBe:7xnx, PDBj:7xnx
PDBsum7xnx
PubMed36259929
UniProtP46779|RL28_HUMAN Large ribosomal subunit protein eL28 (Gene Name=RPL28)

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