Structure of PDB 6zmi Chain Ll

Receptor sequence
>6zmiLl (length=50) Species: 9606 (Homo sapiens) [Search protein sequence]
SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
3D structure
PDB6zmi Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
ChainLl
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Ll S2 S3 H4 K5 K10 L13 K34 I35 R36 Y37 S39 R41 R42 H43 W44 R45 K48 L49 L51 S1 S2 H3 K4 K9 L12 K33 I34 R35 Y36 S38 R40 R41 H42 W43 R44 K47 L48 L50
BS02 rna Ll F7 K15 K18 Q19 R21 I23 W26 I27 M29 K30 T31 I35 K40 F6 K14 K17 Q18 R20 I22 W25 I26 M28 K29 T30 I34 K39
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0002227 innate immune response in mucosa
GO:0006412 translation
GO:0019731 antibacterial humoral response
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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External links
PDB RCSB:6zmi, PDBe:6zmi, PDBj:6zmi
PDBsum6zmi
PubMed32680882
UniProtP62891|RL39_HUMAN Large ribosomal subunit protein eL39 (Gene Name=RPL39)

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