Structure of PDB 8k2c Chain Li

Receptor sequence
>8k2cLi (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
ALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCGFA
PYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAA
AK
3D structure
PDB8k2c Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainLi
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Li R4 G14 H15 V17 R25 H26 S27 R28 R29 R30 G31 R32 L33 T34 H36 R41 Y53 E59 K65 K67 R68 R76 G78 H80 R82 K84 R85 K86 R3 G13 H14 V16 R24 H25 S26 R27 R28 R29 G30 R31 L32 T33 H35 R40 Y52 E58 K64 K66 R67 R75 G77 H79 R81 K83 R84 K85
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k2c, PDBe:8k2c, PDBj:8k2c
PDBsum8k2c
PubMed38942792
UniProtQ9Y3U8|RL36_HUMAN Large ribosomal subunit protein eL36 (Gene Name=RPL36)

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