Structure of PDB 7bhp Chain Lh

Receptor sequence

>7bhpLh (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]

KIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRK
SIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENL
KTKKQQRKERLYPLRKYAV

3D structure

PDB

7bhp Dynamic association of human Ebp1 with the ribosome.

Chain

Resolution

3.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Lh	K74 G75 K77 K79 R89 M91 R93 R94 L95 N96 K97 H98 K106 R109 K110 E111 R112	K72 G73 K75 K77 R87 M89 R91 R92 L93 N94 K95 H96 K104 R107 K108 E109 R110
BS02	rna	Lh	K3 R7 R10 S42 S45 I47 R48 R51 K52 R56 L58 T59 N62 Q63 K66 L81 R84 K86 T88 R89 R92	K1 R5 R8 S40 S43 I45 R46 R49 K50 R54 L56 T57 N60 Q61 K64 L79 R82 K84 T86 R87 R90

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7bhp, PDBe:7bhp, PDBj:7bhp
PDBsum	7bhp
PubMed	33479117
UniProt	P42766\|RL35_HUMAN Large ribosomal subunit protein uL29 (Gene Name=RPL35)