Structure of PDB 6t7i Chain Lg

Receptor sequence

>6t7iLg (length=112) Species: 4932 (Saccharomyces cerevisiae)

AQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPKCGDCGSAL
QGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIIRAFLIEEQKIV
KKVVKEQTEAAK

3D structure

• PDB: 6t7i Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
• Chain: Lg
• Resolution: 3.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Lg	A2 R4 R8 R9 R10 N11 P12 Y13 T15 R16 K24 T25 P26 R31 K36 K37 L38 T40 R41 G45 Q52 G53 I54 S55 T56 R58 P59 R60 Y62 S66 K67 T68 K70 T71 S73 R74 Y76 G78 N83 R91 A92 I95 Q98 K99 K102	A1 R3 R7 R8 R9 N10 P11 Y12 T14 R15 K23 T24 P25 R30 K35 K36 L37 T39 R40 G44 Q51 G52 I53 S54 T55 R57 P58 R59 Y61 S65 K66 T67 K69 T70 S72 R73 Y75 G77 N82 R90 A91 I94 Q97 K98 K101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042254 ribosome biogenesis

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:0030687 preribosome, large subunit precursor
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6t7i, PDBe:6t7i, PDBj:6t7i
• PDBsum: 6t7i
• PubMed: 31858614
• UniProt: P87262|RL34A_YEAST Large ribosomal subunit protein eL34A (Gene Name=RPL34A)