Structure of PDB 8xt1 Chain Ld

Receptor sequence
>8xt1Ld (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
KFTRSRIPEKVFQASPEDHEKYGGDPQNPHKLHIVTRIKSTRRRPYWEKD
IIKMLGLEKAHTPQVHKNIPSVNAKLKVVKHLIRIKPLKLPQGLPAEENM
SNTCLKSTGELVVQWHLKPV
3D structure
PDB8xt1 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainLd
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Ld K35 F36 T37 R38 S39 R71 K73 S74 R76 R77 R78 P79 Y80 K83 M88 K93 A94 K101 S105 K109 K1 F2 T3 R4 S5 R37 K39 S40 R42 R43 R44 P45 Y46 K49 M54 K59 A60 K67 S71 K75
Gene Ontology
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8xt1, PDBe:8xt1, PDBj:8xt1
PDBsum8xt1
PubMed38942792
UniProtQ8TCC3|RM30_HUMAN Large ribosomal subunit protein uL30m (Gene Name=MRPL30)

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