Structure of PDB 6xa1 Chain Lb

Receptor sequence

>6xa1Lb (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]

AKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNK
KGLKKMQANNAKAMSARAEAIKALVASRKLDRLAYIAHPKLGKRARARIA
KGLRLCRPK

3D structure

PDB

6xa1 Selective inhibition of human translation termination by a drug-like compound.

Chain

Resolution

2.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Lb	A2 K3 K5 N6 H7 T8 T9 H10 N11 S13 R14 K15 H17 R18 N19 R25 Q27 R28 Y29 S31 L32 K33 D36 R41 N42 R44 F45 A46 K47 H49 N50 K52 K56 M57 N61 S90 R91 K92 R95 Y98 H101 P102 K103 R107 R111 K114 G115 R117 L118 R120 P121 K122	A1 K2 K4 N5 H6 T7 T8 H9 N10 S12 R13 K14 H16 R17 N18 R24 Q26 R27 Y28 S30 L31 K32 D35 R40 N41 R43 F44 A45 K46 H48 N49 K51 K55 M56 N60 S77 R78 K79 R82 Y85 H88 P89 K90 R94 R98 K101 G102 R104 L105 R107 P108 K109

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

External links

PDB	RCSB:6xa1, PDBe:6xa1, PDBj:6xa1
PDBsum	6xa1
PubMed	33009412
UniProt	P47914\|RL29_HUMAN Large ribosomal subunit protein eL29 (Gene Name=RPL29)