Structure of PDB 8rxx Chain LY

Receptor sequence
>8rxxLY (length=133) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence]
TKFLKPGKVVIVTAGRYAGHKAVIVQNSDVVTKERPYGRALLAGIKKYPK
KVVRGMSKQTIARRSQVGVFLRVVNHKHFLPTRYNVDMSKELRGKINVSD
ASKRSRSKRLVRHVFQARYNAGSSMWFFQRLRF
3D structure
PDB8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
ChainLY
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LY V54 R55 G56 N86 S124 S125 R133 F134 V53 R54 G55 N85 S123 S124 R132 F133
BS02 rna LY G16 R17 R36 Y38 K47 K48 K51 R64 R65 R73 V74 N76 K78 H79 R131 R133 G15 R16 R35 Y37 K46 K47 K50 R63 R64 R72 V73 N75 K77 H78 R130 R132
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxx, PDBe:8rxx, PDBj:8rxx
PDBsum8rxx
PubMed38722744
UniProtQ4Q504

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