Structure of PDB 8xt3 Chain LW

Receptor sequence
>8xt3LW (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]
MARNVVYPLYRLGGPQLRVFRTNFFIQLVRPGVAQPEDTVQFRIPMEMTR
VDLRNYLEGIYNVPVAAVRTRVQHGSNKRRDHRNVRIKKPDYKVAYVQLA
HGQTFTFPDLFPEDDLYSMLEEERQQRQSSDPRRGGVPSWFGL
3D structure
PDB8xt3 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainLW
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LW N4 V6 L9 G32 Q41 T49 R50 V51 R69 R71 Q73 H74 S76 N77 K78 R79 R80 R83 N84 Y96 N4 V6 L9 G32 Q41 T49 R50 V51 R69 R71 Q73 H74 S76 N77 K78 R79 R80 R83 N84 Y96
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0001650 fibrillar center
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0044391 ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8xt3, PDBe:8xt3, PDBj:8xt3
PDBsum8xt3
PubMed38942792
UniProtQ16540|RM23_HUMAN Large ribosomal subunit protein uL23m (Gene Name=MRPL23)

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