Structure of PDB 7mq9 Chain LW

Receptor sequence
>7mq9LW (length=453) Species: 9606 (Homo sapiens) [Search protein sequence]
QDPFPGPAPVPVEVVQKFCRIDKSRKLPHSKAKTRSRLEVAEAEEEETSI
KAARSELLLAEEPGFLEGEDGEDTAKICQADIVEAVDIASAAKHFDLNLR
QFGPYRLNYSRTGRHLAFGGRRGHVAALDWVTKKLMCEINVMEAVRDIRF
LHSEALLAVAQNRWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATAS
ETGFLTYLDVSVGKIVAALNARAGRLDVMSQNPYNAVIHLGHSNGTVSLW
SPAMKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRGTYQP
LSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAGQGKASPPSLEQPYLTH
RLSGPVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSR
KQRQEWEVKALLEKVPAELICLDPRALAEVDVISLEQGKKEQIERLSALD
RFV
3D structure
PDB7mq9 Nucleolar maturation of the human small subunit processome.
ChainLW
Resolution3.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LW R194 R216 Q265 R274 F298 R316 N338 T340 R359 D380 H381 D421 R494 Q498 R100 R122 Q171 R180 F204 R222 N244 T246 R265 D286 H287 D327 R400 Q404
BS02 rna LW V306 E499 K508 V212 E405 K414
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7mq9, PDBe:7mq9, PDBj:7mq9
PDBsum7mq9
PubMed34516797
UniProtO15213|WDR46_HUMAN WD repeat-containing protein 46 (Gene Name=WDR46)

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