Structure of PDB 7zjw Chain LU

Receptor sequence

>7zjwLU (length=180) Species: 9986 (Oryctolagus cuniculus)

SMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLII
RKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRI
LRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKAR
KKLLADQAEARRSKTKEARKRREERLQAKK

3D structure

• PDB: 7zjw Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
• Chain: LU
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LU	S2 M3 L4 R5 K8 R9 G18 K19 K20 K21 W23 L24 P26 S37 R38 Q39 Q40 R42 K43 K46 V55 T56 H58 S59 R60 R62 C63 R64 R71 R74 H75 G77 I78 G79 R81 K82 G83 T84 N86 A87 R88 M89 P90 K92 W95 M96 R97 R100 I101 R103 R104 R108 R110 R117 H118 Y120 H121 Y124 L125 K126 K128 G129 N130 N134 K135 H143	S1 M2 L3 R4 K7 R8 G17 K18 K19 K20 W22 L23 P25 S36 R37 Q38 Q39 R41 K42 K45 V54 T55 H57 S58 R59 R61 C62 R63 R70 R73 H74 G76 I77 G78 R80 K81 G82 T83 N85 A86 R87 M88 P89 K91 W94 M95 R96 R99 I100 R102 R103 R107 R109 R116 H117 Y119 H120 Y123 L124 K125 K127 G128 N129 N133 K134 H142
BS02	rna	LU	R162 R163 R172 R173 R176	R161 R162 R171 R172 R175

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7zjw, PDBe:7zjw, PDBj:7zjw
• PDBsum: 7zjw
• PubMed: 35709277
• UniProt: A0A2J8KH59