Structure of PDB 8fla Chain LS

Receptor sequence
>8flaLS (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
AKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVR
KSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEEN
LKTKKQQRKERLYPLRKYAVKA
3D structure
PDB8fla Principles of human pre-60 S biogenesis.
ChainLS
Resolution2.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LS K5 A6 S45 R48 R51 K52 A55 R56 L58 T59 N62 Q63 K66 R70 L81 K86 T88 R89 R92 K4 A5 S44 R47 R50 K51 A54 R55 L57 T58 N61 Q62 K65 R69 L80 K85 T87 R88 R91
BS02 rna LS Y78 R84 R89 R93 K106 R109 K110 R112 L113 Y77 R83 R88 R92 K105 R108 K109 R111 L112
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:8fla, PDBe:8fla, PDBj:8fla
PDBsum8fla
PubMed37410842
UniProtP42766|RL35_HUMAN Large ribosomal subunit protein uL29 (Gene Name=RPL35)

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