Structure of PDB 7zjw Chain LS

Receptor sequence

>7zjwLS (length=159) Species: 9986 (Oryctolagus cuniculus)

VRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDV
TLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESN
AELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILT
EKEQIVPKP

3D structure

• PDB: 7zjw Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
• Chain: LS
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LS	V2 R3 Y4 R18 G19 S20 H25 F26 K27 R30 Q34 K37 R62 Y63 N64 G65 G66 G68 R69 A71 Q72 K74 Q75 Q80 R82 W83 P84 K85 K86 N97 N101 Q118 V119 R127 Y130 R131 A132 H133 G134 R135 I136 N137 P138 Y139 M140 S141	V1 R2 Y3 R17 G18 S19 H24 F25 K26 R29 Q33 K36 R61 Y62 N63 G64 G65 G67 R68 A70 Q71 K73 Q74 Q79 R81 W82 P83 K84 K85 N96 N100 Q117 V118 R126 Y129 R130 A131 H132 G133 R134 I135 N136 P137 Y138 M139 S140
BS02	rna	LS	S5 R61 R62 W78 N120 K121 P123	S4 R60 R61 W77 N119 K120 P122

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7zjw, PDBe:7zjw, PDBj:7zjw
• PDBsum: 7zjw
• PubMed: 35709277
• UniProt: A0A8J4KQ25