Structure of PDB 6y2l Chain LS

Receptor sequence

>6y2lLS (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]

KASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQL
KKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLT
TAGAVTQCYRDMGARHRARAHSIQIMKVEEIAASKCRRPAVKQFHDSKIK
FPLPHRVLRRQHKPRFTTKRPNTFF

3D structure

PDB

6y2l Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LS	Y63 Q66 V67 F68 K70 R87 S88 H91 Y94 R95 R98 R111 G114 A115 R116 H117 R118 R120 R139 H146 D147 S148 P155 H156 R160 R161 H163 P165 R166 T168 T169 K170 R171 P172 T174 F175 F176	Y62 Q65 V66 F67 K69 R86 S87 H90 Y93 R94 R97 R110 G113 A114 R115 H116 R117 R119 R138 H145 D146 S147 P154 H155 R159 R160 H162 P164 R165 T167 T168 K169 R170 P171 T173 F174 F175
BS02	rna	LS	S42 Y46 S49 K53 K55 S57 R87 H122	S41 Y45 S48 K52 K54 S56 R86 H121

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6y2l, PDBe:6y2l, PDBj:6y2l
PDBsum	6y2l
PubMed	32268098
UniProt	Q02543\|RL18A_HUMAN Large ribosomal subunit protein eL20 (Gene Name=RPL18A)

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