Structure of PDB 8y0u Chain LR

Receptor sequence

>8y0uLR (length=188) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

ANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIV
KKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRV
LRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQR
EKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA

3D structure

PDB

8y0u dormant ribosome with STM1

Chain

Resolution

3.59 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LR	L4 R5 K8 R9 G18 K19 R20 K21 W23 P26 S37 R38 R42 K43 K46 T56 H58 S59 K60 S61 R62 R64 R74 H75 G77 Y78 G79 K80 R81 K82 G83 T84 R85 E86 A87 R88 L89 Q92 W95 L99 R100 R103 R104 R110 K114 H118 Y120 H121 Y124 K125 K128 N130 K135 I143	L3 R4 K7 R8 G17 K18 R19 K20 W22 P25 S36 R37 R41 K42 K45 T55 H57 S58 K59 S60 R61 R63 R73 H74 G76 Y77 G78 K79 R80 K81 G82 T83 R84 E85 A86 R87 L88 Q91 W94 L98 R99 R102 R103 R109 K113 H117 Y119 H120 Y123 K124 K127 N129 K134 I142
BS02	rna	LR	R162 R163 K165 N166 R167 R173 R176	R161 R162 K164 N165 R166 R172 R175

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8y0u, PDBe:8y0u, PDBj:8y0u
PDBsum	8y0u
PubMed	38698775
UniProt	P0CX82\|RL19A_YEAST Large ribosomal subunit protein eL19A (Gene Name=RPL19A)

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