Structure of PDB 7mqa Chain LQ

Receptor sequence
>7mqaLQ (length=830) Species: 9606 (Homo sapiens) [Search protein sequence]
KQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRK
GEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFN
GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQ
ALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEK
RLITGASDSELRVWDIAYLPEDRILSCRKAGSIMREGRDRVVNLAVDKTG
RILACHGTDSVLELFCILSKKEIQKKMDKKMKKARKKAKLHPEVNVEMSL
QDEIQRVTNIKTSAKIKSFDLIHSELKAVFLLQNNLVELYSLNPVRTSRI
TIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYALC
SFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQR
GFVTGGADKSVKFWDFERLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLL
DCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWG
LDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQ
TLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMER
EATVKAAERIMEAIELYREETAKMKEHKAICKNPILMAYGSISPSAYVLE
IFKGIKSSELEESLLVLPFSYVPDILKLFNEFIQLGSDVELICRCLFFLL
RIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMAGLDYLKRECE
AKSEVMFFADATSHLEEKKRKRKKREKLIL
3D structure
PDB7mqa Nucleolar maturation of the human small subunit processome.
ChainLQ
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LQ Q22 K127 E193 W195 R281 K366 R419 K474 Y588 K591 R613 N614 K616 D624 C625 K627 S628 F630 Q18 K123 E189 W191 R240 K317 R360 K415 Y519 K522 R544 N545 K547 D555 C556 K558 S559 F561
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0030515 snoRNA binding
Biological Process
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031965 nuclear membrane
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtQ9UNX4|WDR3_HUMAN WD repeat-containing protein 3 (Gene Name=WDR3)

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