Structure of PDB 8xt0 Chain LN

Receptor sequence
>8xt0LN (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
AIQKMTRVRVVDNSALGNSPYHRAPRCIHVYKKNGVGKVGDQILLAIKGQ
KKKALIVGHCMPGPRMTPRFDSNNVVLIEDNGNPVGTRIKTPIPTSLRKR
EGEYSKVLAIAQNFV
3D structure
PDB8xt0 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainLN
Resolution3.2 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LN Q33 K34 M35 T36 R37 R53 R56 I58 H59 Y61 K63 N64 G79 K81 C90 M91 R95 N103 Q3 K4 M5 T6 R7 R23 R26 I28 H29 Y31 K33 N34 G49 K51 C60 M61 R65 N73
Gene Ontology
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8xt0, PDBe:8xt0, PDBj:8xt0
PDBsum8xt0
PubMed38942792
UniProtQ6P1L8|RM14_HUMAN Large ribosomal subunit protein uL14m (Gene Name=MRPL14)

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