Structure of PDB 8p8m Chain LL

Receptor sequence

>8p8mLL (length=233) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

NPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPP
TIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGKSKQ
DASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKM
GVPYAIVKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFA
DKYDEVKKHWGGGILGNKAQAKMDKRAKNSDSA

3D structure

PDB

8p8m Yeast 60S ribosomal subunit, RPL39 deletion

Chain

Resolution

2.66 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LL	H28 S29 T30 P31 K32 N33 I36 Q38 Q41 P42 R44 L46 S47 R48 Y49 K51 P53 E54 Y55 R60 R68 E100 K105 R108 D124 S126 P129 K133 Y134 G135 L136 N137 H138 A141 L142 N145 V157 P159 L162 K183 A184 K193 T194 S195 G239 N240 K241 A242 K248 R249	H5 S6 T7 P8 K9 N10 I13 Q15 Q18 P19 R21 L23 S24 R25 Y26 K28 P30 E31 Y32 R37 R45 E77 K82 R85 D101 S103 P106 K110 Y111 G112 L113 N114 H115 A118 L119 N122 V134 P136 L139 K160 A161 K170 T171 S172 G216 N217 K218 A219 K225 R226
BS02	rna	LL	Y55 Q59 R60 K63 K181 R185	Y32 Q36 R37 K40 K158 R162

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000470	maturation of LSU-rRNA
GO:0002181	cytoplasmic translation
GO:0006364	rRNA processing

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8p8m, PDBe:8p8m, PDBj:8p8m
PDBsum	8p8m
PubMed
UniProt	P17076\|RL8A_YEAST Large ribosomal subunit protein eL8A (Gene Name=RPL8A)

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