Structure of PDB 5tcu Chain LK

Receptor sequence
>5tcuLK (length=166) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence]
NRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLD
NAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLD
KLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRG
MDIVIVTTANTDEEAR
3D structure
PDB5tcu Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
ChainLK
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LK A70 T76 A69 T75
BS02 rna LK K33 V35 N37 K69 F114 G116 V117 F122 D123 G124 Y143 D144 K32 V34 N36 K68 F113 G115 V116 F121 D122 G123 Y142 D143
BS03 rna LK S24 E27 I60 Q63 K88 S23 E26 I59 Q62 K87
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5tcu, PDBe:5tcu, PDBj:5tcu
PDBsum5tcu
PubMed28487427
UniProtQ2FW18|RL5_STAA8 Large ribosomal subunit protein uL5 (Gene Name=rplE)

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