Structure of PDB 6z6k Chain LJ

Receptor sequence

>6z6kLJ (length=169) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

6z6k Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.

Chain

Resolution

3.4 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LJ	K16 N20 S22 S48 A50 R51 T56 F57 I59 A66 H68 S97 T99 N101 G103 F104 G105 D107 G124 D126 Y128 V130 R140 K142	K11 N15 S17 S43 A45 R46 T51 F52 I54 A61 H63 S92 T94 N96 G98 F99 G100 D102 G119 D121 Y123 V125 R135 K137
BS02	rna	LJ	M9 Q43 T44 V46 T70 R72 G135 R137 V138 R141 T147 G149 N150 S151 H152	M4 Q38 T39 V41 T65 R67 G130 R132 V133 R136 T142 G144 N145 S146 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:6z6k, PDBe:6z6k, PDBj:6z6k
PDBsum	6z6k
PubMed	32687489
UniProt	P0C0W9\|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

[Back to BioLiP]