Structure of PDB 8xt2 Chain LI

Receptor sequence
>8xt2LI (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
TVIVERWWKVPLAGEGRKPRLHRRHRVYKLVEDTKHRPKENLELILTQSV
ENVGVRGDLVSVKKSLGRNRLLPQGLAVYASPENKKLFEEEKLLR
3D structure
PDB8xt2 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainLI
Resolution3.3 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna LI W60 K61 P63 L64 A65 G66 E67 R69 R72 H74 R76 R78 D85 K87 H88 K91 N121 W8 K9 P11 L12 A13 G14 E15 R17 R20 H22 R24 R26 D33 K35 H36 K39 N69
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8xt2, PDBe:8xt2, PDBj:8xt2
PDBsum8xt2
PubMed38942792
UniProtQ9BYD2|RM09_HUMAN Large ribosomal subunit protein bL9m (Gene Name=MRPL9)

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