Structure of PDB 8i9y Chain LG

Receptor sequence

>8i9yLG (length=204) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]

MVKWPEYIRLQRQKKILRMRLKVPPAIAQFQYTLDKNLAAQAFKLLNKYR
PETKQEKKERLLREATAIKEVSKKPYTVKYGLNHVVGLIENKKASLVLIA
NDVDPIELVVFLPALCRKMGIPYAIIKGKARLGTLVHKKTAAVVAITEVR
SEDKNELAKLISAVKEGYLEKVEDTRKRWGGGIMGFKAQKREEKRKKSLE
TAIK

3D structure

PDB

8i9y Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LG	E57 Y58 R60 K108 R111 K131 P132 K136 Y137 G138 L139 H141 G144 N148 K150 D161 P162 L165 A187 K195 K196 T197 A199	E6 Y7 R9 K57 R60 K74 P75 K79 Y80 G81 L82 H84 G87 N91 K93 D104 P105 L108 A130 K138 K139 T140 A142
BS02	rna	LG	Y58 I59 Q62 R63 K66 R69 K87 N88 Q92 K184 K216 S219	Y7 I8 Q11 R12 K15 R18 K36 N37 Q41 K127 K159 S162

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0000470	maturation of LSU-rRNA
GO:0042254	ribosome biogenesis

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8i9y, PDBe:8i9y, PDBj:8i9y
PDBsum	8i9y
PubMed	37129998
UniProt	G0SAJ9

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