Structure of PDB 7n2u Chain LE

Receptor sequence

>7n2uLE (length=178) Species: 83333 (Escherichia coli K-12) [Search protein sequence]

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFRK

3D structure

PDB

7n2u Structural basis of early translocation events on the ribosome.

Chain

Resolution

2.53 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LE	K33 T35 N37 M38 G39 G41 T68 R71 K72 V74 F77 I79 I85 K88 K120 S121 D123 R125 N127 M130 G131 V132 R133 G151 D153 T155 T157	K32 T34 N36 M37 G38 G40 T67 R70 K71 V73 F76 I78 I84 K87 K119 S120 D122 R124 N126 M129 G130 V131 R132 G150 D152 T154 T156
BS02	rna	LE	S24 V25 M26 Q63 K64 L66 K69 K88 V89 T90 R92	S23 V24 M25 Q62 K63 L65 K68 K87 V88 T89 R91

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7n2u, PDBe:7n2u, PDBj:7n2u
PDBsum	7n2u
PubMed	34234344
UniProt	P62399\|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)

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