Structure of PDB 7olc Chain LB

Receptor sequence

>7olcLB (length=387) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]

SHRKYEAPRHGSLAFLPRKRAARHRGRVKSFPKDDPKKPVHLTAAMGYKA
GMTTIVRDLDRPGAKAHKKEVVEAVTIIDCPPMVVVGLVGYIETPRGLRS
LTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYAKKYAENNGASITRELER
IKKYCTVVRVLAHTQIRKTPLKQKKAHLMEIQINGGSVADKVEFGRSLFE
KPVTIDTIFEKDEMIDVIAVTKGHGFVGVTARWGTKKLPRKTHKGLRKVA
CIGAWHPSHVQWTVARAGQMGYHHRTSVNHKIYRIGKGDDEANASTETDL
TKKKITPMGGFVRYGEVNNDYVMIKGSVPGVKKRIMTLRKSLFTHTSRKA
LEKVELKWIDTSSEFGHGAFQTAAEKKQFMGTLKKDL

3D structure

PDB

7olc High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.

Chain

Resolution

2.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	LB	S2 H3 K5 E7 R10 H11 G12 F16 P18 R19 K20 R21 K30 S31 M53 T54 T55 A75 Y92 T95 P96 R97 L99 R100 S101 L102 T104 R116 R117 F118 Y119 K120 N121 Y123 K124 K128 A129 F130 K132 Y133 R151 Y155 R160 R168 Q174 K175 E181 T222 K223 G224 H225 F227 V228 G229 R233 K237 K238 R241 K242 T243 H244 K245 G246 R248 K249 A251 C252 I253 A255 W256 H257 S259 H260 V261 T264 R267 A268 Q270 H275 R276 N280 G310 R314 Y315 K326 S328 V329 R335 F344 F366 H368 M381 K385	S1 H2 K4 E6 R9 H10 G11 F15 P17 R18 K19 R20 K29 S30 M52 T53 T54 A74 Y91 T94 P95 R96 L98 R99 S100 L101 T103 R115 R116 F117 Y118 K119 N120 Y122 K123 K127 A128 F129 K131 Y132 R150 Y154 R159 R167 Q173 K174 E180 T221 K222 G223 H224 F226 V227 G228 R232 K236 K237 R240 K241 T242 H243 K244 G245 R247 K248 A250 C251 I252 A254 W255 H256 S258 H259 V260 T263 R266 A267 Q269 H274 R275 N279 G309 R313 Y314 K325 S327 V328 R334 F343 F365 H367 M380 K384
BS02	MG	LB	S2 H3	S1 H2

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7olc, PDBe:7olc, PDBj:7olc
PDBsum	7olc
PubMed	35079002
UniProt	G0RXW1

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