Structure of PDB 8xt1 Chain L3

Receptor sequence
>8xt1L3 (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
AAALARLGLRPVKQVRVQFCPFEKNVESTRTFLQTVSSEKVRSTNLNCSV
IADVRHDGSEPCVDVLFGDGHRLIMRGAHLTALEMLTAFASHIRAR
3D structure
PDB8xt1 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainL3
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna L3 K41 L84 K40 L83
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8xt1, PDBe:8xt1, PDBj:8xt1
PDBsum8xt1
PubMed38942792
UniProtQ96EL3|RM53_HUMAN Large ribosomal subunit protein mL53 (Gene Name=MRPL53)

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