Structure of PDB 7tos Chain L27

Receptor sequence

>7tosL27 (length=75) Species: 562 (Escherichia coli) [Search protein sequence]

RNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLF
AKADGKVKFEVKGPKNRKFISIEAE

3D structure

PDB

7tos Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.

Chain

L27

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	L27	N8 R10 D11 S12 E13 A14 K15 R16 L17 K20 R21 F22 G23 E25 L28 A29 G30 S31 I32 R37 G38 T39 K40 F41 G50 R51 D52 H53 F56 F65 R73	N2 R4 D5 S6 E7 A8 K9 R10 L11 K14 R15 F16 G17 E19 L22 A23 G24 S25 I26 R31 G32 T33 K34 F35 G44 R45 D46 H47 F50 F59 R67
BS02	rna	L27	G69 P70 N72	G63 P64 N66

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

External links

PDB	RCSB:7tos, PDBe:7tos, PDBj:7tos
PDBsum	7tos
PubMed	35589706
UniProt	P0A7L8\|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)